Dynamics of leukocyte inflammatory markers in patients with ST-elevation myocardial infarction depending on left ventricle ejection fraction

Aim: to evaluate the dynamics of leukocyte inflammatory markers in patients with ST-elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI) depending on ejection fraction left ventricular (LV). Material and methods. The study group consisted 23 consecutive STEMI admitted Regional Clinical Cardiology Center Chernivtsi, who underwent successful reperfusion treatment by PCI. To markers, a complete blood count (CBC) was assessed at admission, day 10 hospital stay background optimal drug therapy. Results. It found that reduced (LVEF) (group 2) admission had significantly higher (P < 0.05) an increase absolute neutrophils 0.01) markers: neutrophil-to-lymphocyte ratio (NLR) 0.01), monocyte-to-lymphocyte (MLR), systemic immune inflammation index (SII) response (SIRI) aggregate (AISI) 0.05), integrated (III) 0.05). On treatment, analysis showed 2, NLR SII remained than preserved LVEF 1). At changes leukocyte-based under influence therapy PCI, decrease NLR, MLR, SII, SIRI, IIII, LMR were observed. Conclusions. CBC identifies risk adverse cardiovascular events determines measures regulate activity process STEMI.